Pen resting on paper with highlighted text

Publications

2024

  • LaFleur, M.W., Lemmen, A.M., Streeter, I.S.L., Nguyen, T.H., Milling, L.E., Derosia, N.M., Hoffman, Z.M., Gillis, J.E., Tjokrosurjo, Q., Markson, S.C., Huang, A.Y., Anekal, P.V., Montero Llopis, P., Haining, W.N., Doench, J.G. and Sharpe, A.H. (2024). X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system. Nature Immunology, 25(1), pp. 178–188. Available at: https://doi.org/10.1038/s41590-023- 01689-6.
  • Gordon, W.E., Baek, S., Nguyen, H.P., Kuo, Y.-M., Bradley, R., Fong, S.L., Kim, N., Galazyuk, A., Lee, I., Ingala, M.R., Simmons, N.B., Schountz, T., Cooper, L.N., Georgakopoulos-Soares, I., Hemberg, M. and Ahituv, N. (2024). Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas. Nature Communications, 15(1), p. 12. Available at: https://doi.org/10.1038/s41467-023-44186-y.
  • Suh, J., Kim, H., Min, J., Yeon, H.J., Hemberg, M., Scimeca, L., Wu, M.-R., Kang, H.G., Kim, Y.-J. and Kim, J.-H. (2024). Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis. Cell Reports Medicine, 5(1), p. 101342. Available at: https://doi.org/10.1016/j.xcrm.2023.101342.
  • Joller, N., Anderson, A.C. and Kuchroo, V.K. (2024). LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation. Immunity, 57(2), pp. 206–222. Available at: https://doi.org/10.1016/j.immuni.2024.01.010.
  • Wang, Y., Cho, J.-W., Kastrunes, G., Buck, A., Razimbaud, C., Culhane, A.C., Sun, J., Braun, D.A., Choueiri, T.K., Wu, C.J., Jones, K., Nguyen, Q.-D., Zhu, Z., Wei, K., Zhu, Q., Signoretti, S., Freeman, G.J., Hemberg, M. and Marasco, W.A. (2024). Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model. iScience, 27(2). Available at: https://doi.org/10.1016/j.isci.2024.108879.
  • Lee, H.-G., Rone, J.M., Li, Z., Akl, C.F., Shin, S.W., Lee, J.-H., Flausino, L.E., Pernin, F., Chao, C.-C., Kleemann, K.L., Srun, L., Illouz, T., Giovannoni, F., Charabati, M., Sanmarco, L.M., Kenison, J.E., Piester, G., Zandee, S.E.J., Antel, J.P., Rothhammer, V., Wheeler, M.A., Prat, A., Clark, I.C. and Quintana, F.J. (2024). Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature, 627(8005), pp. 865–872. Available at: https://doi. org/10.1038/s41586-024-07187-5.
  • Wheeler, M. (2024). Interactions between immune cells recorded. Nature, 627(8003), pp. 277–279.
  • Cho, J.-W., Cao, J. and Hemberg, M. (2024). Joint analysis of mutational and transcriptional landscapes in human cancer reveals key perturbations during cancer evolution. Genome Biology, 25(1), p. 65. Available at: https://doi. org/10.1186/s13059-024-03201-1.
  • Dixon, K.O., Lahore, G.F. and Kuchroo, V.K. (2024). Beyond T cell exhaustion: TIM-3 regulation of myeloid cells. Science Immunology, 9(93), p. eadf2223. Available at: https://doi.org/10.1126/sciimmunol.adf2223.
  • Rone, J.M., Faust Akl, C. and Quintana, F.J. (2024). Astrocyte control of brain metastasis. Developmental Cell, 59(5), pp. 559–560. Available at: https://doi.org/10.1016/j.devcel.2024.02.004.
  • Qi, L., Iskols, M., Shi, D., Reddy, P., Walker, C., Lezgiyeva, K., Voisin, T., Pawlak, M., Kuchroo, V.K., Chiu, I.M., Ginty, D.D. and Sharma, N. (2024). A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell, 187(6), pp. 1508-1526.e16. Available at: https://doi.org/10.1016/j. cell.2024.02.006.
  • Milling, L.E., Markson, S.C., Tjokrosurjo, Q., Derosia, N.M., Streeter, I.S.L., Hickok, G.H., Lemmen, A.M., Nguyen, T.H., Prathima, P., Fithian, W., Schwartz, M.A., Hacohen, N., Doench, J.G., LaFleur, M.W. and Sharpe, A.H. (2024). Framework for in vivo T cell screens. The Journal of Experimental Medicine, 221(4), p. e20230699. Available at: https://doi.org/10.1084/jem.20230699.
  • Yuan, C.U., Quah, F.X. and Hemberg, M. (2024). Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing. Molecular Aspects of Medicine, 96, p. 101255. Available at: https://doi. org/10.1016/j.mam.2024.101255.
  • Abnizova, I., Stapel, C., Boekhorst, R. te, Lee, J.T.H. and Hemberg, M. (2024). Integrative analysis of transcriptomic and epigenomic data reveals distinct patterns for developmental and housekeeping gene regulation. BMC Biology, 22(1), p. 78. Available at: https://doi.org/10.1186/s12915-024-01869-2.
  • Cadinu, P., Sivanathan, K.N., Misra, A., Xu, R.J., Mangani, D., Yang, E., Rone, J.M., Tooley, K., Kye, Y.-C., Bod, L., Geistlinger, L., Lee, T., Mertens, R.T., Ono, N., Wang, G., Sanmarco, L., Quintana, F.J., Anderson, A.C., Kuchroo, V.K., Moffitt, J.R. and Nowarski, R. (2024). Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling. Cell, 187(8), pp. 2010-2028.e30. Available at: https://doi.org/10.1016/j. cell.2024.03.013.
  • Neavin, D., Senabouth, A., Arora, H., Lee, J.T.H., Ripoll-Cladellas, A., Franke, L., Prabhakar, S., Ye, C.J., McCarthy, D.J., Melé, M., Hemberg, M., Powell, J.E., and sc-eQTLGen Consortium (2024). Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods. Genome Biology, 25(1), p. 94. Available at: https://doi.org/10.1186/s13059-024-03224-8.
  • Tooley, K., Jerby, L., Escobar, G., Krovi, S.H., Mangani, D., Dandekar, G., Cheng, H., Madi, A., Goldschmidt, E., Lambden, C., Krishnan, R.K., Rozenblatt-Rosen, O., Regev, A. and Anderson, A.C. (2024). Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity. Cell Reports Medicine, 5(7). Available at: https://doi.org/10.1016/j.xcrm.2024.101640.
To top